I have a fair few favourites in each genre. I do make it a point to watch flicks that star certain people, especially when the film has two or more actors that play off each other well. Pairs like Jack Lemmon with Walter Matthau, with Matthew McConaughey, Kate Hudson, and Owen Wilson with Vince Vaughn make my must-see list for the most part.
@RandyW, Nicholas Cage is so hit-or-miss that it's unreal. I've never seen him give a mediocre performance. What's the best character you've seen him portray?